We do not have enough data on this route to provide a reliable graph showing how many days before departure it is the best to book.
However, usually the closer it is to the departure, the more expensive the tickets are.
The most popular airlines on the route Tehran Imam Khomeini - Milan Malpensa: Ukraine International (PS).
There is no direct flight on the route from Tehran Imam Khomeini to Milan Malpensa
Il volo con scalo più breve dura 14h 25min.