We do not have enough data on this route to provide a reliable graph showing how many days before departure it is the best to book.
However, usually the closer it is to the departure, the more expensive the tickets are.
The most popular airlines on the route Palermo - Madrid: Alitalia (AZ), Iberia (IB).
The cheapest flights are on the route Punta Raisi (PMO) - Barajas (MAD).
There is no direct flight on the route from Palermo to Madrid
Il volo con scalo più breve dura 24h 30min.