Your travel platformSkip navigation
Santa Cruz de la Sierra

Santiago de Chile Santa Cruz de la Sierra - Cheap flights

Special flight deals from Santiago de Chile to Santa Cruz de la Sierra

    Why book flights with eSky?

    Largest choice of flights

    With flights from over 500 airlines, we'll find your perfect match in seconds.

    Flexible search

    Extend your search to include nearby airports and flex your dates for the cheapest deals.

    Excellent products and services

    Need travel insurance, cancellation insurance, car hire, local attraction bookings or more? We have you covered.

    Over 4950 customer reviews - choose proven quality and book with complete confidence.

    Find the best time to book cheap flights to Santa Cruz de la Sierra

    Flexible on travel dates? Discover the cheapest month to fly to Santa Cruz de la Sierra

    • Cheapest round-trip flight

      from 389 USD

    • Cheapest month to travel

      September

    • The cheapest day to fly

      Saturday

    • Lowest prices

      30 days before
    Jun
    475 USD
    Jul
    410 USD
    Aug
    410 USD
    Sep
    389 USD
    Oct
    407 USD
    Nov
    415 USD
    Dec
    408 USD
    Jan
    418 USD
    Feb
    408 USD
    Mar
    536 USD
    Apr
    435 USD
    May
    ??

    When is the best time to buy flight tickets?

    Find out how far in advance it's worth booking round-trip flights.

    • 6 months before

      from

      470 USD

    • 3 months before

      from

      318 USD

    • 30 days before

      from

      279 USD

    • 7 days before

      from

      411 USD

    Discover the cheapest day to fly

    Discover on which day of the week flights are usually the most affordable.
    329 USD
    Mon
    405 USD
    Tue
    377 USD
    Wed
    417 USD
    Thu
    325 USD
    Fri
    310 USD
    Sat
    360 USD
    Sun

    General information

    • Local time (UTC-4)

    • Flight time from Santiago de Chile

    • Exchange Rate

      1 BOB = 0.14 USD
    Santa Cruz de la Sierra
    Santa Cruz de la Sierra is the largest city in Bolivia, located in the eastern part of the country along the Piraí River. As the capital of the Santa Cruz Department, the city is an important economic and cultural hub. Founded in 1561 by Ñuflo de Chávez, it has undergone many relocations. Renowned for its colonial architecture and lush vegetation, it attracts tourists year-round. The average temperature is about 24 °C, with the best time to visit being from May to October.