For the cheapest flights to Madrid book 6 days before departure.
The most popular airlines on the route Prague - Madrid: Smart Wings (QS), Czech Airlines (OK), Iberia (IB).
The cheapest flights are on the route Ruzyne (PRG) - Barajas (MAD).
Direct flights last about 2h 54min.
Direct flights are available 7 days a week.
Direct flights: Smart Wings (QS), Czech Airlines (OK), Iberia (IB).